USP5 Mouse Monoclonal Antibody [Clone ID: LBI1F8]

• Background:

  Ubiquitin (see MIM 191339) -dependent proteolysis is a complex pathway of protein metabolism implicated in such diverse cellular functions as maintenance of chromatin structure, receptor function, and degradation of abnormal proteins. A late step of the process involves disassembly of the polyubiquitin chains on degraded proteins into ubiquitin monomers. USP5 disassembles branched polyubiquitin chains by a sequential exo mechanism, starting at the proximal end of the chain (Wilkinson et al., 1995 [PubMed 7578059]) . [supplied by OMIM]

• Synonyms:

  ISOT

• Gene Name:

  Ubiquitin specific peptidase 5

• Gene ID:

  8078

• UniProt:

  P45974

• Conjugation:

  Unconjugated

• Concentration:

  0.7 mg/ml

• Dilution:

  WB 1:1000~2000, IHC 1:50

• Form:

  PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome, Protease

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  USP5

• Overview:

  Anti-USP5 mouse monoclonal antibody, clone LBI1F8

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=8078

• Uniprot URL:

  https://www.uniprot.org/uniprot/P45974