ID2 Mouse Monoclonal Antibody [Clone ID: LBI9A8]

• Background:

  The protein encoded by this gene belongs to the inhibitor of DNA binding (ID) family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the ID family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by suppressing their heterodimerization partners through the HLH domains. This protein may play a role in negatively regulating cell differentiation. A pseudogene has been identified for this gene.

• Synonyms:

  BHLHb26; GIG8; ID2A; ID2H

• Gene Name:

  Inhibitor of DNA binding 2

• Gene ID:

  3398

• UniProt:

  Q02363

• Conjugation:

  Unconjugated

• Related Pathways:

  TGF-beta signaling pathway

• Field of Research:

  TGF-beta signaling pathway

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:500, IHC 1:50, IF 1:100

• Form:

  PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  ES Cell Differentiation/IPS, Stem cell relevant signaling - TGFb/BMP signaling pathway, Transcription Factors

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  ID2

• Overview:

  ID2 mouse monoclonal antibody, clone LBI9A8

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=3398

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q02363