C-Myc (MYC) Mouse Monoclonal Antibody [Clone ID: LBI1A6]

• Background:

  C-Myc is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.

• Synonyms:

  BHLHe39; c-Myc; MRTL; MYCC

• Gene Name:

  MYC proto-oncogene, bHLH transcription factor

• Gene ID:

  4609

• UniProt:

  P01106

• Conjugation:

  Unconjugated

• Related Pathways:

  Acute myeloid leukemia, Bladder cancer, Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Jak-STAT signaling pathway, MAPK signaling pathway, Pathways in cancer, Small cell lung cancer, TGF-beta signaling pathway, Thyroid cancer, Wnt signaling pathway

• Field of Research:

  Acute myeloid leukemia, Bladder cancer, Cell cycle, Chronic myeloid leukemia, Colorectal cancer, Endometrial cancer, ErbB signaling pathway, Jak-STAT signaling pathway, MAPK signaling pathway, Pathways in cancer, Small cell lung cancer, TGF-beta signaling pathway, Thyroid cancer, Wnt signaling pathway

• Concentration:

  1 mg/ml

• Dilution:

  WB 1:2000, IHC 1:50, IF 1:100, FLOW 1:100

• Form:

  PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Buffer:

  PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.

• Function:

  Druggable Genome, Embryonic stem cells, Induced pluripotent stem cells, Stem cell - Pluripotency, Stem cell relevant signaling - JAK/STAT signaling pathway, Stem cell relevant signaling - TGFb/BMP signaling pathway, Stem cell relevant signaling - Wnt Signaling pathway, Transcription Factors

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Symbol:

  MYC

• Overview:

  C-Myc (c-Myc) mouse monoclonal antibody, clone LBI1A6

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=4609

• Uniprot URL:

  https://www.uniprot.org/uniprot/P01106