(DANRE) rab11fip4a Antibody (Center) [APR33323G]

• Background:

  Tissue Location: Isoform 1 is predominantly expressed in neural tissues. Isoform B is expressed ubiquitously. In the developing retina, it is expressed in progenitors throughout the retina at early stages and becomes restricted to the ganglion cell layer and ciliary marginal zone as differentiation proceeds.

• Synonyms:

  Rab11 family-interacting protein 4A, FIP4-Rab11, Rab11-FIP4-A, zRab11-FIP4-A, rab11fip4a, rab11fip4

• Gene Name:

  Rab11fip4a

• Gene ID:

  436806

• UniProt:

  Q3LGD4

• Chromosomal Location:

  Recycling endosome membrane; Peripheral membrane protein. Cleavage furrow. Midbody. Cytoplasmic vesicle. Note=Recruited to the cleavage furrow and the midbody during cytokinesis.

• Applications:

  WB

• Dilution:

  WB--1:1000

• Function:

  Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abcission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cytokinesis (By similarity) . May play a role in differentiation during retinal development.

• Molecular Weight:

  70946

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality (DANRE) rab11fip4a Antibody (Center) [APR33323G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=436806

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q3LGD4