B3GNT5 Antibody (Center) [APR32721G]

• Background:

  Tissue Location: Widely expressed. Highly expressed in lung, colon, placenta, testis, pituitary gland and cerebellum. Weakly expressed in brain, liver, spleen, lymph node and thymus

• Synonyms:

  Lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase, Lactotriaosylceramide synthase, Lc (3) Cer synthase, Lc3 synthase, UDP-GlcNAc:beta-Gal beta-1,3-N-acetylglucosaminyltransferase 5, BGnT-5, Beta-1,3-Gn-T5, Beta-1,3-N-acetylglucosaminyltransferase 5, Beta3Gn-T5, B3GNT5

• Gene Name:

  HGNC:15684

• Gene ID:

  84002

• UniProt:

  Q9BYG0

• Chromosomal Location:

  Golgi apparatus membrane; Single- pass type II membrane protein

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Beta-1,3-N-acetylglucosaminyltransferase that plays a key role in the synthesis of lacto- or neolacto-series carbohydrate chains on glycolipids, notably by participating in biosynthesis of HNK-1 and Lewis X carbohydrate structures. Has strong activity toward lactosylceramide (LacCer) and neolactotetraosylceramide (nLc (4) Cer; paragloboside), resulting in the synthesis of Lc (3) Cer and neolactopentaosylceramide (nLc (5) Cer), respectively. Probably plays a central role in regulating neolacto-series glycolipid synthesis during embryonic development.

• Molecular Weight:

  44053

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality B3GNT5 Antibody (Center) [APR32721G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=84002

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9BYG0