CYP1B1 Antibody (Center) [APR32518G]

• Background:

  Tissue Location: Expressed in heart, brain, lung, skeletal muscle, kidney, spleen, thymus, prostate, testis, ovary, small intestine, colon, and peripheral blood leukocytes (PubMed:8175734) . Expressed in retinal endothelial cells and umbilical vein endothelial cells (at protein level) (PubMed:19005183) .

• Synonyms:

  Cytochrome P450 1B1, CYPIB1, CYP1B1

• Gene Name:

  CYP1B1 {ECO:0000303|PubMed:8910454, ECO:0000312|HGNC:HGNC:2597}

• Gene ID:

  1545

• UniProt:

  Q16678

• Chromosomal Location:

  Endoplasmic reticulum membrane {ECO:0000250|UniProtKB:Q64429}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q64429}. Microsome membrane {ECO:0000250|UniProtKB:Q64429}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q64429}. Mitochondrion {ECO:0000250|UniProtKB:Q64429}. Note=Located primarily in endoplasmic reticulum. Upon treatment with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), CYP1B1 is also targeted to mitochondria {ECO:0000250|UniProtKB:Q64429}

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

• Function:

  209729971155582812865317106813761525811020972997115558281286531710681376152581101155582812865317104268141068137615258110209729972106819510426814

• Molecular Weight:

  60846

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality CYP1B1 Antibody (Center) [APR32518G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=1545

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q16678