ORC2L Antibody (Center) [APR31264G]

• Synonyms:

  Origin recognition complex subunit 2, ORC2, ORC2L

• Gene Name:

  ORC2

• Gene ID:

  4999

• UniProt:

  Q13416

• Chromosomal Location:

  Nucleus.

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3. Stabilizes LRWD1, by protecting it from ubiquitin-mediated proteasomal degradation. Also stabilizes ORC3.

• Molecular Weight:

  65972

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ORC2L Antibody (Center) [APR31264G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=4999

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q13416