GFRA4 Antibody (Center) [APR31094G]

• Background:

  Tissue Location: Predominantly expressed in the adult thyroid gland. Low levels also found in fetal adrenal and thyroid glands

• Synonyms:

  GDNF family receptor alpha-4, GDNF receptor alpha-4, GDNFR-alpha-4, GFR-alpha-4, Persephin receptor, GFRA4

• Gene Name:

  GFRA4

• Gene ID:

  64096

• UniProt:

  Q9GZZ7

• Chromosomal Location:

  [Isoform GFRalpha4a]: Cell membrane; Lipid- anchor, GPI-anchor [Isoform GFRalpha4c]: Secreted.

• Applications:

  WB

• Dilution:

  WB--1:1000

• Form:

  Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

• Function:

  Receptor for persephin. Mediates the GDNF-induced autophosphorylation and activation of the RET receptor. May be important in C-cell development and, in the postnatal development of the adrenal medulla.

• Molecular Weight:

  31670

• Storage Conditions:

  Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GFRA4 Antibody (Center) [APR31094G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=64096

• Uniprot URL:

  https://www.uniprot.org/uniprot/Q9GZZ7