UBE2C Antibody (C-term) [AMM22275G]

• Synonyms:

  Ubiquitin-conjugating enzyme E2 C, 6.3.2.19, UbcH10, Ubiquitin carrier protein C, Ubiquitin-protein ligase C, UBE2C, UBCH10

• Gene Name:

  UBE2C

• Gene ID:

  11065

• UniProt:

  O00762

• Applications:

  WB

• Dilution:

  WB--1:2000

• Function:

  Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.

• Molecular Weight:

  19652

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality UBE2C Antibody (C-term) [AMM22275G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=11065

• Uniprot URL:

  https://www.uniprot.org/uniprot/O00762