RASSF2 Antibody (Center) [ApR04840G]

• Background:

  Tissue Location: Widely expressed with highest levels in brain, placenta, peripheral blood and lung. Frequently down-regulated in lung tumor cell lines.

• Synonyms:

  Ras association domain-containing protein 2, RASSF2, KIAA0168

• Gene Name:

  RASSF2

• Gene ID:

  9770

• UniProt:

  P50749

• Chromosomal Location:

  Nucleus. Cytoplasm. Chromosome, centromere, kinetochore. Note=Translocates to the cytoplasm in the presence of STK3/MST2 AND STK4/MST1

• Applications:

  WB

• Dilution:

  WB--1:2000

• Function:

  Potential tumor suppressor. Acts as a KRAS-specific effector protein. May promote apoptosis and cell cycle arrest. Stabilizes STK3/MST2 by protecting it from proteasomal degradation.

• Molecular Weight:

  37790

• Storage Conditions:

  Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

• Overview:

  We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RASSF2 Antibody (Center) [ApR04840G].

• Gene ID URL:

  https://www.ncbi.nlm.nih.gov/gene/?term=9770

• Uniprot URL:

  https://www.uniprot.org/uniprot/P50749