Interferon alpha 2/IFNA2 Protein, Mouse, Recombinant

• Background:

  IFNA2 (Interferon Alpha 2) is a Protein Coding gene. This gene is a member of the alpha interferon gene cluster on chromosome 9. The encoded protein is a cytokine produced in response to viral infection. Type I Interferons (IFNs) are well-known cytokines that exert antiviral activity, antitumor activity, and immunomodulatory effects. Interferon tau (IFNT), a type I IFN similar to alpha IFNs (IFNA), is the pregnancy recognition signal produced by the ruminant conceptus. Among the IFN-α genes, a total of 28 different sequence variants have been described. The three principal subtypes of IFNα-2 are designated α-2a, α-2b, and α-2c. IFNα-2b is being the predominant allele while IFNα-2a is less predominant and IFNα-2c only a minor allelic variant.

• Synonyms:

  Ifa2 Protein, Mouse

• Gene Name:

  Interferon, alpha 2

• Expression System:

  Yeast

• Tag:

  No tag

• Endotoxin:

  Please contact us for more information.

• Purity:

  > 95 % as determined by SDS-PAGE.

• Activity:

  Measured in antiviral assays using L929 cells infected with vesicular stomatitisvirus (VSV) .The EDfor this effect is 0.15-0.9ng/mL.

• Form:

  Lyophilized

• Buffer:

  Lyophilized from sterile PBS, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.

• Function:

  Cytokine Proteins, Growth Factor proteins, Biological Target proteins

• Molecular Weight:

  The recombinant mouse Ifna2 consists 167 amino acids and predicts a molecular mass of 19.4 kDa.

• Storage Conditions:

  In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

• Symbol:

  IFNA2

• Species:

  Mouse

• Protein ID:

  NP_034633.2

• Overview:

  A DNA sequence encoding the mouse Ifna2 (NP_034633.2) (Cys24-Glu190) was expressed.

• AA Sequence:

  Cys24-Glu190

• Protein ID Link:

  https://www.ncbi.nlm.nih.gov/protein/NP_034633.2