Products for Research Use Only
RegisterLogin

CHN1 Protein, Human, Recombinant

CAT: 0882-PH52158I0Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0882-PH52158I0Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
CHN1, also known as chimerin 1, is a TPase-activating protein for ras-related p21-rac and a phorbol ester receptor. It is predominantly expressed in neurons, and plays an important role in neuronal signal-transduction mechanisms. CHN1 is involved in the assembly of neuronal locomotor circuits as a direct effector of EPHA4 in axon guidance. The CHN1 gene provides instructions for making two very similar proteins called α1-chimaerin and α2-chimaerin. These proteins play an important role in the early development of the nervous system. In particular, they help regulate complex chemical signaling pathways during the formation and development of nerve cells (neurons) . These proteins help guide the growth of axons and dendrites, which are specialized extensions of neurons that transmit and receive nerve impulses throughout the nervous system.
Overview
A DNA sequence encoding the human CHN1 (NP_001813.1) (Ala2-Phe459) was fused with two additional amino acids (Gly&Pro) at the N-terminus.
Synonyms
ARHGAP2 Protein, Human; CHN Protein, Human; DURS2 Protein, Human; NC Protein, Human; RHOGAP2 Protein, Human
Gene Name
Chimerin 1
Expression System
Baculovirus-Insect Cells
Tag
No tag
Endotoxin
< 1.0 EU per μg of the protein as determined by the LAL method.
Purity
> 90 % as determined by SDS-PAGE.
Activity
At Leading Biology, the biological activity of a recombinant protein is routinely measured using a bioassay, e.g. chemotaxis or cell proliferation assay, enzyme assay, or a functional ELISA. When a recombinant protein is an enzyme, specific activity is derived from an enzymatic assay. Each enzyme is tested for potency by cleavage of a substrate. We are in the process of updating the biological activity data. If you have any questions regarding this update, please feel free to contact our technical support team.
Form
Lyophilized
Buffer
Lyophilized from sterile 20mM Tris, 500mM NaCl, 10% glycerol, pH 7.4. Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
Molecular Weight
The recombinant human CHN1 consists of 460 amino acids and has a calculated molecular mass of 53.2 kDa. The recombinant protein migrates as an approximately 45 kDa band in SDS-PAGE under reducing conditions.
Storage Conditions
In general, recombinant proteins are provided as lyophilized powder which are shipped at ambient temperature. Bulk packages of recombinant proteins are provided as frozen liquid. They are shipped out with blue ice unless customers require otherwise. Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CHN1
Species
Human
Protein ID
NP_001813.1
AA Sequence
Ala2-Phe459
Protein ID Link
https://www.ncbi.nlm.nih.gov/protein/NP_001813.1

Related Products

CatalogName
PH34279M5CHN 1 (CHN1) (NM_001822) Human Recombinant Protein
PH41053M5CHN 1 (CHN1) (NM_001025201) Human Recombinant Protein
PM47184M5Chn1 (NM_175752) Mouse Recombinant Protein
LH19653VCHN 1 (CHN1) (NM_001822) Human Over-expression Lysate
LH04230VCHN 1 (CHN1) (NM_001025201) Human Over-expression Lysate
APR27487N-01CHN1 Rabbit pAb (APR27487N)
AMM12932VCFCHN 1 (CHN1) Mouse Monoclonal Antibody [Clone ID: LBI3C6]
AMM12962VCHN 1 (CHN1) Mouse Monoclonal Antibody [Clone ID: LBI2E11]
AMM12921VCHN 1 (CHN1) Mouse Monoclonal Antibody [Clone ID: LBI2A1]
APR11581G-01CHN1 Antibody (N-term) [APR11581G]

Alternative Products

CatalogName
TMPY-03793-01CHN1 Protein, Human, Recombinant
RP007036CHN1 Recombinant Protein (Human)
E30P65520ARecombinant Human CHN1 Protein
RP123983CHN1 Recombinant Protein (Mouse)
RP194882CHN1 Recombinant Protein (Rat)
TMPY-03792-01CHN1 Protein, Human, Recombinant (His & GST)
MBS139422-01Human CHN1 Protein Lysate
TP504946Chn1 (NM_175752) Mouse Recombinant Protein
MBS8121785-01CHN1 Protein, Human, Recombinant (His & GST Tag)
PROTP15882CHN 1 (CHN1) (NM_001025201) Human Recombinant Protein

Popular Products