TCF4 Antibody - N-terminal region: Biotin (P100776_P050-Biotin)

• Gene Name:

  Transcription factor 4

• Gene Aliases:

  E2-2, ITF2, PTHS, SEF2, CDG2T, FECD3, ITF-2, SEF-2, TCF-4, SEF2-1, SEF2-1A, SEF2-1B, SEF2-1D, bHLHb19

• Gene ID:

  6925

• Swiss Prot:

  P15884

• Accession Number:

  NP_003190

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Guinea Pig, Horse, Pig

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human TCF4

• Target:

  TCF4 encodes transcription factor 4, a basic helix-turn-helix transcription factor. The protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. TCF4 is expressed predominantly in pre-B-cells, although it is found in other tissues as well.TCF4 encodes transcription factor 4, a basic helix-turn-helix transcription factor. The protein recognizes an Ephrussi-box ('E-box') binding site ('CANNTG') - a motif first identified in immunoglobulin enhancers. TCF4 is expressed predominantly in pre-B-cells, although it is found in other tissues as well. TCF4 is known to produce multiple transcripts; however as the complete structure is only known for the transcript that encodes the b isoform, that is the variant presented here.

• Partner Proteins:

  GOLGA8F; REXO1L6P; FAM74A4; GOLGA8EP; C9orf171; RAB41; SEC14L4; NEK8; ZDHHC24; MSRB3; FERD3L; PPP1R18; NUDT10; PATE1; TMEM213; KLC3; ZNF417; NEU4; NR2C2AP; POLR1A; SZT2; EPB41L3; MAPKBP1; SLC4A1AP; FRS3; NEK6; GLRX3; MAD2L2; BCAS2; TSSC4; CHAF1A; POLR1C

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Concentration:

  0.5 mg/mL

• Homology:

  Guinea Pig: 92%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  71kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  667

• NCBI Gene Symbol:

  TCF4

• Protein Name:

  Transcription factor 4

• Nucleotide Accession Number:

  NM_003199