TIMD4 Antibody : HRP (OAPB00415-HRP)

• Gene Name:

  T-cell immunoglobulin and mucin domain-containing protein 4

• Gene Aliases:

  TIM4, SMUCKLER

• Gene ID:

  91937

• Swiss Prot:

  Q96H15

• Accession Number:

  NP_001140198.1NP_612388.2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  The immunogen for anti-TIM-4 antibody: antibody was raised against a 16 amino acid peptide from near the center of human TIM-4.

• Target:

  (IN) T cell immunoglobulin and mucin domain containing protein 4

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  ELISA, WB, ICC, IF

• Purification:

  Affinity chromatography purified via peptide column

• Concentration:

  0.6-0.7 mg/ml

• Homology:

  Human; Mouse

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• References & Citations:

  Meyers JH, Sabatos CA, Chakravarti S, et al. The TIM family regulates autoimmune and allergic diseases. Trends Mol. Med. 2005; 11:362-9.;
  Meyers JH, Chakravarti S, Schlesinger D, et al. TIM-4 is the ligand for TIM-1, and the TIM-1-TIM4 interaction regulates T cell proliferation. Nat. Immunol. 2005; 6:455-64.;
  Kuchroo VK, Umetsu DT, DeKruyff RH, et al. The TIM gene family: emerging roles in immunity and disease. Nat. Rev. Immunol. 2003; 3:454-62.;
  Shakhov AN, Rybtsov S, Tumanov AV, et al. SMUCKLER/TIM4 is a distinct member of TIM family expressed by stromal cells of secondary lymphoid tissues and associated with lymphotoxin signaling.

• Shipping Conditions:

  Wet Ice

• Applications Notes:

  TIM-1 antibody can be used for the detection of TIM-1 by Western blot at 1 ug/mL. Antibody can also be used for immunohistochemistry starting at 10 ug/mL. For immunofluorescence start at 20 ug/mL.

• NCBI Gene Symbol:

  TIMD4

• NCBI GB Accession Number:

  TIMD4

• Host or Source:

  Rabbit

• Protein Name:

  T-cell immunoglobulin and mucin domain-containing protein 4

• Nucleotide Accession Number:

  NM_001146726.1NM_138379.2