LITAF Antibody - N-terminal region: FITC (ARP74033_P050-FITC)

• Gene Aliases:

  PIG7, SIMPLE, TP53I7

• Gene ID:

  9516

• Swiss Prot:

  Q99732-2

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N-terminal region of Human LITAF

• Target:

  Lipopolysaccharide is a potent stimulator of monocytes and macrophages, causing secretion of tumor necrosis factor-alpha (TNF-alpha) and other inflammatory mediators. This gene encodes lipopolysaccharide-induced TNF-alpha factor, which is a DNA-binding protein and can mediate the TNF-alpha expression by direct binding to the promoter region of the TNF-alpha gene. The transcription of this gene is induced by tumor suppresor p53 and has been implicated in the p53-induced apoptotic pathway. Mutations in this gene cause Charcot-Marie-Tooth disease type 1C (CMT1C) and may be involved in the carcinogenesis of extramammary Paget's disease (EMPD) . Multiple alternatively spliced transcript variants have been found for this gene.

• Partner Proteins:

  REEP6; UBQLN1; STAM2; CALCOCO2; BAG3; HGS; UBC; STAT6; ATXN1; ITCH; TSG101; NEDD4; ELAVL1; RADIL; SMAD2; COMT

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  25kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  228

• NCBI Gene Symbol:

  LITAF