SP100 Antibody - middle region: FITC (ARP72581_P050-FITC)

• Gene Aliases:

  Lysp100b

• Gene ID:

  6672

• Swiss Prot:

  P23497

• Accession Number:

  NP_003104

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of Human SP100

• Target:

  This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia) -SP100 nuclear bodies. PML and SP100 are covalently modified by the SUMO-1 modifier, which is considered crucial to nuclear body interactions. The encoded protein binds heterochromatin proteins and is thought to play a role in tumorigenesis, immunity, and gene regulation. Alternatively spliced variants have been identified for this gene; one of which encodes a high-mobility group protein.

• Partner Proteins:

  RBM39; DYRK2; SUMO1; UBE2I; SP100; SUMO2; SUMO3; PHC1; DNMT3A; ACTN2; RTP5; L3MBTL3; TRAF3IP3; GIPC2; AMOTL2; ZC2HC1A; SENP1; CBX5; USPL1; UBC; PML; VPS25; PUS1; CRTAP; TOM1L1; SERPINE2; AGL; CREM; DSTN; AHCYL1; SEC23A; IGBP1; ETS1; ARID3A; TERF2IP; TERF2

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  96kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  879

• NCBI Gene Symbol:

  SP100