RPLP2 Antibody - N-terminal region: HRP (ARP66087_P050-HRP)

• Gene Aliases:

  P2, LP2, RPP2, D11S2243E

• Gene ID:

  6181

• Swiss Prot:

  P05387

• Accession Number:

  NP_000995

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N-terminal region of Human RPLP2

• Target:

  Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal phosphoprotein that is a component of the 60S subunit. The protein, which is a functional equivalent of the E. coli L7/L12 ribosomal protein, belongs to the L12P family of ribosomal proteins. It plays an important role in the elongation step of protein synthesis. Unlike most ribosomal proteins, which are basic, the encoded protein is acidic. Its C-terminal end is nearly identical to the C-terminal ends of the ribosomal phosphoproteins P0 and P1. The P2 protein can interact with P0 and P1 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

• Partner Proteins:

  TP53; AURKA; TUBGCP4; CEP250; TUBGCP2; CEP57; UBC; TUBG1; MDM2; CNDP2; NANS; NPEPPS; RPL23; FBXO6; YWHAQ; IGSF8; ICAM1; CD81; PAN2; MAPK8; FN1; UBL4A; PA2G4; CTNNB1; HNRNPA3; RPLP0P6; RPS27L; RPL14; UBA52; RPS28; RPS26; RPS25; RPS24; RPS23; RPS21; RPS20

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Sample Type:

  RPLP2 is strongly supported by BioGPS gene expression data to be expressed in OVCAR3

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 92%; Goat: 79%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 79%; Zebrafish: 79%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  12kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  115

• NCBI Gene Symbol:

  RPLP2

• Protein Name:

  60S acidic ribosomal protein P2

• Nucleotide Accession Number:

  NM_001004