TP53I3 Antibody - C-terminal region: Biotin (ARP64532_P050-Biotin)

• Gene Name:

  Tumor protein p53 inducible protein 3

• Gene Aliases:

  PIG3

• Gene ID:

  9540

• Swiss Prot:

  Q53FA7

• Accession Number:

  NP_004872

• Host:

  Rabbit

• Reactivity:

  Human, Cow, Dog, Horse, Pig, Rabbit

• Target:

  The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer.

• Partner Proteins:

  TLDC1; PLK1; UBC; TP53BP1; H2AFX; EEF1G; UBR1; FUNDC2; UNC119; TP53

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Sample Type:

  TP53I3 is supported by BioGPS gene expression data to be expressed in HepG2

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 93%; Dog: 93%; Horse: 93%; Human: 100%; Pig: 93%; Rabbit: 86%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  35kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  332

• NCBI Gene Symbol:

  TP53I3

• Protein Name:

  Quinone oxidoreductase PIG3

• Nucleotide Accession Number:

  NM_004881