TCP1 Antibody - C-terminal region: FITC (ARP63619_P050-FITC)

• Gene Name:

  T-complex 1

• Gene Aliases:

  CCT1, CCTa, D6S230E, CCT-alpha, TCP-1-alpha

• Gene ID:

  6950

• Swiss Prot:

  P17987

• Accession Number:

  NP_110379

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

• Target:

  The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC) . This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized. In addition, three pseudogenes that appear to be derived from this gene have been found.

• Partner Proteins:

  FUS; ERLIN2; HUWE1; CBFA2T2; UBC; TP53; NEDD1; VHL; TUBG1; SUMO2; LGALS3BP; CDC20; STAU1; INPP5K; CDC5L; VRK2; PPP4C; COPA; COPG1; USP9X; PARK2; FBXO6; YWHAQ; UBD; FBXW4; FBXO46; STK25; HDAC6; HDAC3; NPM1; ILK; CDK5; CDK2; PAN2; US3; FAM86B2; CFAP52; METT

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Sample Type:

  TCP1 is strongly supported by BioGPS gene expression data to be expressed in HeLa

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  61kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  556

• NCBI Gene Symbol:

  TCP1

• Protein Name:

  T-complex protein 1 subunit alpha

• Nucleotide Accession Number:

  NM_030752