CTSL1 Antibody - C-terminal region: HRP (ARP63239_P050-HRP)

• Gene Name:

  Cathepsin L1

• Gene Aliases:

  MEP, CATL, CTSL1

• Gene ID:

  1514

• Swiss Prot:

  P07711

• Accession Number:

  NP_666023

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Sheep

• Target:

  The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. At least two transcript variants encoding the same protein have been found for this gene.

• Partner Proteins:

  SGTA; SERPINB3; BTN3A3; RELB; PPP1CC; APOA1; ALB; UBC; EED; BAG6; GEM; ARSA; SERPINB13; CST3; CST7; CTSC; CSTB; KNG1; PLAU; TG; CD7; CSTA; RXRA; CXCL8; IGFBP3; CD74; GCG; COL18A1; CUX1; CTSL; SLPI

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Human: 100%; Mouse: 77%; Rat: 77%; Sheep: 77%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  36kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  333

• NCBI Gene Symbol:

  CTSL

• Protein Name:

  Cathepsin L1

• Nucleotide Accession Number:

  NM_145918