HLA-E Antibody - C-terminal region: FITC (ARP62847_P050-FITC)

• Gene Name:

  Major histocompatibility complex, class I, E

• Gene Aliases:

  QA1, HLA-6.2

• Gene ID:

  3133

• Swiss Prot:

  P13747

• Accession Number:

  NP_005507

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Pig

• Target:

  HLA-E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin) . The heavy chain is anchored in the membrane. HLA-E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1 and alpha2 domains, which both bind the peptide, exon 4 encodes the alpha3 domain, exon 5 encodes the transmembrane region, and exons 6 and 7 encode the cytoplasmic tail.

• Partner Proteins:

  UBC; CALR; TAP2; UBD; PPP1R16A; KLRD1; KLRC2; CD8A; KLRC1; HLA-E; B2M

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Human: 100%; Mouse: 100%; Pig: 92%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  38kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  358

• NCBI Gene Symbol:

  HLA-E

• Protein Name:

  HLA class I histocompatibility antigen, alpha chain E

• Nucleotide Accession Number:

  NM_005516