MRPL3 Antibody - N-terminal region: HRP (ARP62688_P050-HRP)

• Gene Name:

  Mitochondrial ribosomal protein L3

• Gene Aliases:

  MRL3, RPML3, COXPD9

• Gene ID:

  11222

• Swiss Prot:

  P09001

• Accession Number:

  NP_009139

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

• Target:

  Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein that belongs to the L3P ribosomal protein family. A pseudogene corresponding to this gene is found on chromosome 13q.

• Partner Proteins:

  UBC; MRPS27; mug82; ICT1; C1QBP; MRPL55; MRPL10; MRPL52; MRPL9; MRPL41; MRPS9; MRPL17; MRPL39; MRPL4; MRPL13; MRPL42; MRPL46; MRPL19; RPS18; RPS15; MRPL12; MRPL23; NDUFS3; APP; CAND1

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 79%; Rabbit: 93%; Rat: 93%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  38kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  348

• NCBI Gene Symbol:

  MRPL3

• Protein Name:

  39S ribosomal protein L3, mitochondrial

• Nucleotide Accession Number:

  NM_007208