CTPS2 Antibody - N-terminal region : Biotin (ARP62443_P050-Biotin)

• Gene Name:

  CTP synthase II

• Gene Aliases:

  DKFZp686C17207, FLJ43358, MGC32997

• Gene ID:

  56474

• Swiss Prot:

  Q9NRF8

• Accession Number:

  NP_787055

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Zebrafish

• Target:

  The protein encoded by this gene catalyzes the formation of CTP from UTP with the concomitant deamination of glutamine to glutamate. This protein is the rate-limiting enzyme in the synthesis of cytosine nucleotides, which play an important role in various metabolic processes and provide the precursors necessary for the synthesis of RNA and DNA. Cancer cells that exhibit increased cell proliferation also exhibit an increased activity of this encoded protein. Thus, this protein is an attractive target for selective chemotherapy. Three alternatively spliced transcript variants encoding the same protein have been described for this gene.

• Partner Proteins:

  CTPS2; SPG21; RNF2; LRSAM1; EHD4; EHD1; PLIN3; MTMR2; WARS; PRKDC; NUCB1; METTL1; KTN1; HSF1; GTF2I; DHPS; RPL37A; RPL23A; FGFR1; CTBP2; UBC; SUMO2; OTUD5

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  IHC, WB

• Purification:

  Affinity Purified

• Sample Type:

  CTPS2 is supported by BioGPS gene expression data to be expressed in HeLa

• Concentration:

  0.5 mg/ml

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  64kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  586

• NCBI Gene Symbol:

  CTPS2

• NCBI GB Accession Number:

  CTPS2

• Host or Source:

  Rabbit

• Protein Name:

  CTP synthase 2

• Nucleotide Accession Number:

  NM_175859

• Peptide Sequence:

  AKRENFCNIHVSLVPQLSATGEQKTKPTQNSVRALRGLGLSPDLIVCRSS