HSD17B8 Antibody - N-terminal region: Biotin (ARP62143_P050-Biotin)

• Gene Name:

  Hydroxysteroid (17-beta) dehydrogenase 8

• Gene Aliases:

  KE6, FABG, HKE6, FABGL, RING2, H2-KE6, SDR30C1, D6S2245E, dJ1033B10.9

• Gene ID:

  7923

• Swiss Prot:

  Q92506

• Accession Number:

  NP_055049

• Host:

  Rabbit

• Reactivity:

  Human

• Target:

  In mice, the Ke6 protein is a 17-beta-hydroxysteroid dehydrogenase that can regulate the concentration of biologically active estrogens and androgens. It is preferentially an oxidative enzyme and inactivates estradiol, testosterone, and dihydrotestosterone. However, the enzyme has some reductive activity and can synthesize estradiol from estrone. The protein encoded by this gene is similar to Ke6 and is a member of the short-chain dehydrogenase superfamily. An alternatively spliced transcript of this gene has been detected, but the full-length nature of this variant has not been determined.

• Partner Proteins:

  RAD21

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Sample Type:

  HSD17B8 is supported by BioGPS gene expression data to be expressed in RPMI 8226

• Concentration:

  0.5 mg/mL

• Homology:

  Human: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  29kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  261

• NCBI Gene Symbol:

  HSD17B8

• Protein Name:

  Estradiol 17-beta-dehydrogenase 8

• Nucleotide Accession Number:

  NM_014234