HYAL3 Antibody - C-terminal region: HRP (ARP61904_P050-HRP)

• Gene Name:

  Hyaluronoglucosaminidase 3

• Gene Aliases:

  LUCA3, HYAL-3, LUCA-3

• Gene ID:

  8372

• Swiss Prot:

  O43820

• Accession Number:

  NP_003540

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep

• Target:

  This gene encodes a member of the hyaluronidase family. Hyaluronidases are endoglycosidase enzymes that degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. The regulated turnover of hyaluronan plays a critical role in many biological processes including cell proliferation, migration and differentiation. The encoded protein may also play an important role in sperm function. This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression, and the expression of specific transcript variants may be indicative of tumor status.

• Partner Proteins:

  DAB1; SLC22A2

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 90%; Dog: 90%; Guinea Pig: 86%; Horse: 100%; Human: 100%; Mouse: 93%; Pig: 90%; Rabbit: 79%; Rat: 86%; Sheep: 90%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  46kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  417

• NCBI Gene Symbol:

  HYAL3

• Protein Name:

  Hyaluronidase-3

• Nucleotide Accession Number:

  NM_003549