F11R Antibody - C-terminal region: HRP (ARP61361_P050-HRP)

• Gene Name:

  F11 receptor

• Gene Aliases:

  JAM, KAT, JAM1, JAMA, JCAM, CD321, PAM-1

• Gene ID:

  50848

• Swiss Prot:

  Q9Y624

• Accession Number:

  NP_058642

• Host:

  Rabbit

• Reactivity:

  Human, Cow, Dog, Pig, Rabbit

• Target:

  Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is an important regulator of tight junction assembly in epithelia. In addition, the encoded protein can act as (1) a receptor for reovirus, (2) a ligand for the integrin LFA1, involved in leukocyte transmigration, and (3) a platelet receptor. Multiple 5' alternatively spliced variants, encoding the same protein, have been identified but their biological validity has not been established.

• Partner Proteins:

  SGTA; PEX19; BDNF; ELAVL1; UBC; PICK1; F11R; CGN; MPDZ; PARD3; F2RL2; TJP1; ASIP; CASK; PRKCA; PTPRB; MLLT4; ITGAL; CSNK2A1

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Sample Type:

  F11R is supported by BioGPS gene expression data to be expressed in HeLa

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 85%; Dog: 92%; Human: 100%; Pig: 92%; Rabbit: 100%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  33kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  299

• NCBI Gene Symbol:

  F11R

• Protein Name:

  Junctional adhesion molecule A

• Nucleotide Accession Number:

  NM_016946