GET4 Antibody - C-terminal region: HRP (ARP61197_P050-HRP)

• Gene Name:

  Golgi to ER traffic protein 4 homolog (S. cerevisiae)

• Gene Aliases:

  CEE, TRC35, CGI-20, C7orf20

• Gene ID:

  51608

• Swiss Prot:

  Q7L5D6-2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Guinea Pig, Yeast

• Immunogen:

  The immunogen is a synthetic peptide directed towards the C-terminal region of Human GET4

• Target:

  GET4 is a component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting.

• Partner Proteins:

  HUWE1; PRKAB2; FAF1; VAPB; SGTA; UBC; RABEP2; LSM8; MTA2; CSTF2; FAF2; BAG6; UBL4A; VCP; EXOC2; SEC61B; TRA; AMFR; KEAP1; TMEM256; KIAA1377; ATP5H; KIFC2; EEF1G; UBAC2; SNCAIP; PLK1; PRKCSH; KAT5; TTR; PTMS; SOD2; CDKN1A; CAPNS1; WRAP73

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Guinea Pig: 77%; Human: 100%; Mouse: 77%; Rat: 77%; Yeast: 77%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  30kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  274

• NCBI Gene Symbol:

  GET4

• Protein Name:

  Golgi to ER traffic protein 4 homolog