CYB5R3 Antibody - C-terminal region: FITC (ARP60822_P050-FITC)

• Gene Name:

  Cytochrome b5 reductase 3

• Gene Aliases:

  B5R, DIA1

• Gene ID:

  1727

• Swiss Prot:

  P00387

• Accession Number:

  NP_000389

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the C terminal region of human CYB5R3

• Target:

  This gene encodes cytochrome b5 reductase, which includes a membrane-bound form in somatic cells (anchored in the endoplasmic reticulum, mitochondrial and other membranes) and a soluble form in erythrocytes. The membrane-bound form exists mainly on the cytoplasmic side of the endoplasmic reticulum and functions in desaturation and elongation of fatty acids, in cholesterol biosynthesis, and in drug metabolism. The erythrocyte form is located in a soluble fraction of circulating erythrocytes and is involved in methemoglobin reduction. The membrane-bound form has both membrane-binding and catalytic domains, while the soluble form has only the catalytic domain. Alternate splicing results in multiple transcript variants. Mutations in this gene cause methemoglobinemias.

• Partner Proteins:

  SUMO2; PARK2; UBC; SLC1A5; SDHA; RPS7; HSPA1L; CDK2; SPP1; CYB5R3; CYB5A; HBG2; CYCS; ESR1

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 93%; Rabbit: 86%; Rat: 86%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  34kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  301

• NCBI Gene Symbol:

  CYB5R3

• Protein Name:

  NADH-cytochrome b5 reductase 3

• Nucleotide Accession Number:

  NM_000398