COL4A6 Antibody - middle region: Biotin (ARP60012_P050-Biotin)

• Gene Name:

  Collagen, type IV, alpha 6

• Gene Aliases:

  DFNX6, DELXq22.3, CXDELq22.3

• Gene ID:

  1288

• Swiss Prot:

  Q14031

• Accession Number:

  NP_001838

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human COL4A6

• Target:

  This gene encodes one of the six subunits of type IV collagen, the major structural component of basement membranes. Like the other members of the type IV collagen gene family, this gene is organized in a head-to-head conformation with another type IV collagen gene, alpha 5 type IV collagen, so that the gene pair shares a common promoter. Deletions in the alpha 5 gene that extend into the alpha 6 gene result in diffuse leiomyomatosis accompanying the X-linked Alport syndrome caused by the deletion in the alpha 5 gene. Two splice variants have been identified for this gene.

• Partner Proteins:

  APP; VHL; HABP2; MATN2; SERPINE2; OSM; FBLN2; FN1; DCN; CD93; MMP9

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Human: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  161kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  1691

• NCBI Gene Symbol:

  COL4A6

• Protein Name:

  Collagen alpha-6 (IV) chain

• Nucleotide Accession Number:

  NM_001847