MERTK Antibody - N-terminal region: HRP (ARP59019_P050-HRP)

• Gene Name:

  C-mer proto-oncogene tyrosine kinase

• Gene Aliases:

  MER, RP38, c-Eyk, c-mer, Tyro12

• Gene ID:

  10461

• Swiss Prot:

  Q12866

• Accession Number:

  NP_006334

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Horse, Pig, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N-terminal region of Human MERTK

• Target:

  This gene is a member of the MER/AXL/TYRO3 receptor kinase family and encodes a transmembrane protein with two fibronectin type-III domains, two Ig-like C2-type (immunoglobulin-like) domains, and one tyrosine kinase domain. Mutations in this gene have been associated with disruption of the retinal pigment epithelium (RPE) phagocytosis pathway and onset of autosomal recessive retinitis pigmentosa (RP) .

• Partner Proteins:

  UBC; HSP90AA1; TNK2; MERTK; ITGB5; NEDD4L; IKBKG; LMO4; BMPR2; GAS6; VAV1; GRB2

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 79%; Dog: 93%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 93%; Rat: 93%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  109kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  999

• NCBI Gene Symbol:

  MERTK

• Protein Name:

  Tyrosine-protein kinase Mer