MAPK1 Antibody - C-terminal region: Biotin (ARP58899_P050-Biotin)

• Gene Name:

  Mitogen-activated protein kinase 1

• Gene Aliases:

  ERK, p38, p40, p41, ERK2, ERT1, NS13, ERK-2, MAPK2, PRKM1, PRKM2, P42MAPK, p41mapk, p42-MAPK

• Gene ID:

  5594

• Swiss Prot:

  P28482

• Accession Number:

  NP_620407

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Rabbit, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the C terminal region of human MAPK1

• Target:

  The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. The activation of this kinase requires its phosphorylation by upstream kinases. Upon activation, this kinase translocates to the nucleus of the stimulated cells, where it phosphorylates nuclear targets. Two alternatively spliced transcript variants encoding the same protein, but differing in the UTRs, have been reported for this gene.

• Partner Proteins:

  Eif4ebp1; ATF2; RPS6KA3; RAF1; PTGDR; MAP2K6; MAP2K1; MAPK3; HDAC6; TP53; NEDD8; DGCR8; HMGB1; NAV1; PDCD6IP; CEP350; MAPK12; RPS6KA2; MAPK1; PDE4D; MBP; KRAS; SQSTM1; CUEDC2; GAB2; BRAF; RPS6KA1; MAP2K4; MAP2K2; ELK1; NOXA1; TIAL1; GADD45A; MAP3K10; SMAD

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Sample Type:

  MAPK1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  41kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  360

• NCBI Gene Symbol:

  MAPK1

• Protein Name:

  Mitogen-activated protein kinase 1

• Nucleotide Accession Number:

  NM_138957