FKBP2 Antibody - N-terminal region: Biotin (ARP58465_P050-Biotin)

• Gene Name:

  FK506 binding protein 2, 13kDa

• Gene Aliases:

  FKBP13, PPIase, FKBP-13

• Gene ID:

  2286

• Swiss Prot:

  P26885

• Accession Number:

  NP_004461

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Goat, Guinea Pig, Horse, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human FKBP2

• Target:

  FKBP2 is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. Multiple alternatively spliced variants, encoding the same protein, have been identified.The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is thought to function as an ER chaperone and may also act as a component of membrane cytoskeletal scaffolds. This gene has two alternatively spliced transcript variants that encode the same isoform. Multiple polyadenylation sites have been described for this gene, but the full length nature of this gene has not been determined.

• Partner Proteins:

  UBQLN1; RAB3C; VAMP2; RAB6A; UBC; BARD1; UBQLN4; PTGES3; RAP2A; MAPK3; ARFGEF1; EPB41L2; BAG6; EPB41; C1QC; ARFGEF2; CDKN2A

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Sample Type:

  FKBP2 is supported by BioGPS gene expression data to be expressed in 721_B

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Goat: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rat: 100%; Zebrafish: 79%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  16kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  142

• NCBI Gene Symbol:

  FKBP2

• Protein Name:

  Peptidyl-prolyl cis-trans isomerase FKBP2

• Nucleotide Accession Number:

  NM_004470