CAPNS1 Antibody - middle region: FITC (ARP58434_P050-FITC)

• Gene Name:

  Calpain, small subunit 1

• Gene Aliases:

  CANP, CDPS, CSS1, CANPS, CAPN4, CALPAIN4

• Gene ID:

  826

• Swiss Prot:

  P04632

• Accession Number:

  NP_001003962

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit, Sheep

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human CAPNS1

• Target:

  Calpains are a ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. Calpain families have been implicated in neurodegenerative processes, as their activation can be triggered by calcium influx and oxidative stress. Calpain I and II are heterodimeric with distinct large subunits associated with common small subunits, all of which are encoded by different genes. This gene encodes a small subunit common to both calpain I and II and is associated with myotonic dystrophy. Two transcript variants encoding the same protein have been identified for this gene.

• Partner Proteins:

  AGTRAP; HUWE1; NEDD1; TUBGCP2; TUBGCP3; CDC20; UBC; OGFOD1; STK26; ISOC1; DCPS; MAT2B; PROSC; FERMT2; YWHAQ; PDIA4; YWHAZ; YWHAH; YWHAG; YWHAE; PTMA; PPP1CA; PAK2; PAFAH1B1; MYO1E; MAT2A; GNAI3; GAPDH; EIF5; TBCB; ALDH7A1; ASNS; APEX1; ADRB2; PPARGC1A; VC

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 93%; Guinea Pig: 93%; Horse: 93%; Human: 100%; Mouse: 93%; Pig: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  29kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  268

• NCBI Gene Symbol:

  CAPNS1

• Protein Name:

  Calpain small subunit 1

• Nucleotide Accession Number:

  NM_001003962