GREM2 Antibody - N-terminal region: Biotin (ARP57635_P050-Biotin)

• Gene Name:

  Gremlin 2

• Gene Aliases:

  PRDC, DAND3, STHAG9, CKTSF1B2

• Gene ID:

  64388

• Swiss Prot:

  Q9H772

• Accession Number:

  NP_071914

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog, Guinea Pig, Horse

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human GREM2

• Target:

  This gene encodes a member of the BMP (bone morphogenic protein) antagonist family. Like BMPs, BMP antagonists contain cystine knots and typically form homo- and heterodimers. The CAN (cerberus and dan) subfamily of BMP antagonists, to which this gene belongs, is characterized by a C-terminal cystine knot with an eight-membered ring. The antagonistic effect of the secreted glycosylated protein encoded by this gene is likely due to its direct binding to BMP proteins. As an antagonist of BMP, this gene may play a role in regulating organogenesis, body patterning, and tissue differentiation.

• Partner Proteins:

  BMP4; BMP2

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Dog: 93%; Guinea Pig: 100%; Horse: 93%; Human: 100%; Mouse: 100%; Rat: 93%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  17kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  168

• NCBI Gene Symbol:

  GREM2

• Protein Name:

  Gremlin-2

• Nucleotide Accession Number:

  NM_022469