MMP26 Antibody - C-terminal region: FITC (ARP57558_P050-FITC)

• Gene Name:

  Matrix metallopeptidase 26

• Gene Aliases:

  MGC126590, MGC126592

• Gene ID:

  56547

• Swiss Prot:

  Q9NRE1

• Accession Number:

  NP_068573

• Host:

  Rabbit

• Reactivity:

  Human, Rat

• Immunogen:

  The immunogen is a synthetic peptide directed towards the C terminal region of human MMP26

• Target:

  Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The encoded protein degrades type IV collagen, fibronectin, fibrinogen, casein, vitronectin, alpha 1-antitrypsin, alpha 2-macroglobulin, and insulin-like growth factor-binding protein 1, and activates MMP9 by cleavage. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain.

• Partner Proteins:

  SERPINA1; IGFBP1; MMP9

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Sample Type:

  MMP26 is supported by BioGPS gene expression data to be expressed in A549

• Concentration:

  0.5 mg/mL

• Homology:

  Human: 100%; Rat: 83%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  19kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  261

• NCBI Gene Symbol:

  MMP26

• Protein Name:

  Matrix metalloproteinase-26

• Nucleotide Accession Number:

  NM_021801