PRKACB Antibody - N-terminal region: FITC (ARP56415_P050-FITC)

• Gene Name:

  Protein kinase, cAMP-dependent, catalytic, beta

• Gene Aliases:

  CAFD2, PKACB, PKA C-beta

• Gene ID:

  5567

• Swiss Prot:

  P22694

• Accession Number:

  NP_997461

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human PRKACB

• Target:

  CAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is a member of the Ser/Thr protein kinase family and is a catalytic subunit of cAMP-dependent protein kinase.

• Partner Proteins:

  APPBP2; UBC; TP53RK; TPRKB; KIAA1279; ARPC2; ACTR2; ACTR3; ARPC1B; ARPC4; SUMO1; PFDN1; CDK5RAP2; MAPRE1; AKAP11; DCAF7; AKAP9; TRAP1; PDE4DIP; AKAP5; AKAP7; VAPA; VAPB; DYNLL1; AKAP1; RPS6; RPL27A; PRKAR2B; PRKAR2A; PRKAR1B; PRKAR1A; PRKACA; HSP90AB1; HS

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  28kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  257

• NCBI Gene Symbol:

  PRKACB

• Protein Name:

  CAMP-dependent protein kinase catalytic subunit beta

• Nucleotide Accession Number:

  NM_207578