PYDC1 Antibody - N-terminal region : FITC (ARP55560_P050-FITC)

• Gene Name:

  PYD (pyrin domain) containing 1

• Gene Aliases:

  ASC2, POP1, PYC1, cPOP1

• Gene ID:

  260434

• Swiss Prot:

  Q8WXC3

• Accession Number:

  NP_690865

• Host:

  Rabbit

• Reactivity:

  Human, Cow, Dog, Goat, Guinea Pig, Horse, Yeast

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N-terminal region of Human PYDC1

• Target:

  PYDC1 associates with apoptosis-associated specklike protein containing a CARD domain (ASC) and modulates its ability to collaborate with pyrin and cryopyrin in NF-kappa-B and pro- caspase-1 activation. It suppresses kinase activity of NF-kappa-B inhibitor kinase (IKK) complex, expression of NF-kappa-B inducible genes and inhibits NF-kappa-B activation by cytokines and LPS.

• Partner Proteins:

  WDR82

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/ml

• Homology:

  Cow: 83%; Dog: 83%; Goat: 83%; Guinea Pig: 85%; Horse: 83%; Human: 100%; Yeast: 77%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  9kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  89

• NCBI Gene Symbol:

  PYDC1

• NCBI GB Accession Number:

  PYDC1

• Host or Source:

  Rabbit

• Protein Name:

  Pyrin domain-containing protein 1

• Peptide Sequence:

  REAILKVLENLTPEELKKFKMKLGTVPLREGFERIPRGALGQLDIVDLTD