GNAO1 Antibody - N-terminal region : FITC (ARP55424_P050-FITC)

• Gene Name:

  Guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O

• Gene Aliases:

  GNAO, DEE17, NEDIM, EIEE17, HLA-DQB1, G-ALPHA-o

• Gene ID:

  2775

• Swiss Prot:

  P09471

• Accession Number:

  NP_620073

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human GNAO1

• Target:

  Activated Goalpha interacted directly with PLZF, and enhanced its function as a transcriptional and cell growth suppressor. Goalpha might play a role in mediating extracellular signal-regulated kinase activation by G protein-coupled receptors in the brain

• Partner Proteins:

  UBC; ADRA2A; BAG3; Htt; RGS9; GABBR1; Haus4; RGS1; RIC8A; DCTN2; KLHL3; SCN8A; PDE6G; CRHR1; GPSM2; HRH4; NGB; S1PR5; RGS19; GRM6; FFAR2; TSHR; RGS5; RGS10; RGS7; RGS4; RGS16; RGS14; PTPRU; CCR5; NUCB1; PDE6H; CACNA1B; OPRM1; OPRD1; GNAO1; GNAI1; ADRA2C

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/ml

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 93%; Horse: 100%; Human: 100%; Mouse: 79%; Rabbit: 100%; Rat: 93%; Sheep: 100%; Zebrafish: 93%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  40kDa

• References & Citations:

  Won, J.H., (2008) Cell. Signal. 20 (5), 884-891

• Shipping Conditions:

  Wet Ice

• Protein Length:

  354

• NCBI Gene Symbol:

  GNAO1

• NCBI GB Accession Number:

  GNAO1

• Host or Source:

  Rabbit

• Protein Name:

  Guanine nucleotide-binding protein G (o) subunit alpha

• Nucleotide Accession Number:

  NM_138736

• Peptide Sequence:

  PVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRMEDTEPF

• Subunit:

  Alpha