FGFR1OP Antibody - N-terminal region: Biotin (ARP53669_P050-Biotin)

• Gene Name:

  FGFR1 oncogene partner

• Gene Aliases:

  FOP, FGFR1OP

• Gene ID:

  11116

• Swiss Prot:

  O95684

• Accession Number:

  NP_919410

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Pig, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human FGFR1OP

• Target:

  FGFR1OP is a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t (6;8) (q27; p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage.This gene encodes a largely hydrophilic protein postulated to be a leucine-rich protein family member. A t (6;8) (q27; p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. This gene is thought to play an important role in normal proliferation and differentiation of the erythroid lineage. Alternatively spliced transcript variants that encode different proteins have been identified.

• Partner Proteins:

  CEP19; VASP; BRCA1; WRNIP1; ABL1; UBC; NAGK; FGFR1OP; CEP350; PACS1; PPP2R1A; PPP2R1B; PPP2CB; PPP2CA

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Sample Type:

  There is BioGPS gene expression data showing that FGFR1OP is expressed in HeLa

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 93%; Dog: 93%; Guinea Pig: 86%; Horse: 93%; Human: 100%; Mouse: 86%; Pig: 93%; Rabbit: 93%; Rat: 93%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  41kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  379

• NCBI Gene Symbol:

  FGFR1OP

• Protein Name:

  FGFR1 oncogene partner

• Nucleotide Accession Number:

  NM_194429