MRPL10 Antibody - N-terminal region: FITC (ARP52830_P050-FITC)

• Gene Name:

  Mitochondrial ribosomal protein L10

• Gene Aliases:

  L10MT, MRPL8, RPML8, MRP-L8, MRP-L10

• Gene ID:

  124995

• Swiss Prot:

  Q7Z7H8

• Accession Number:

  NP_660298

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Dog, Guinea Pig, Horse, Pig, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human MRPL10

• Target:

  Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 5q. Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 5q.

• Partner Proteins:

  FAM9B; KLHL12; PNMA1; TCF4; REL; UBC; NPM1; MRPL1; MRPL11; MRPL41; MRPL15; MRPL13; MRPL3; MRPL12; MRPL23; SLC25A3; ILF3; ICT1; HNRNPU; ABCC2; BCS1L; APP; ABCB7; MRPL10; USP22

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Dog: 83%; Guinea Pig: 77%; Horse: 83%; Human: 100%; Mouse: 85%; Pig: 85%; Rabbit: 92%; Rat: 77%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  29kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  261

• NCBI Gene Symbol:

  MRPL10

• Protein Name:

  39S ribosomal protein L10, mitochondrial

• Nucleotide Accession Number:

  NM_145255