DNAAF4 Antibody - C-terminal region: Biotin (ARP52547_P050-Biotin)

• Gene Name:

  Dynein axonemal assembly factor 4

• Gene Aliases:

  RD, DYX1, EKN1, DYXC1, CILD25, DYX1C1

• Gene ID:

  161582

• Swiss Prot:

  Q8WXU2

• Accession Number:

  NP_570722

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the C terminal region of human DYX1C1

• Target:

  This gene encodes a tetratricopeptide repeat domain-containing protein. The encoded protein interacts with estrogen receptors and the heat shock proteins, Hsp70 and Hsp90. An homologous protein in rat has been shown to function in neuronal migration in the developing neocortex. A chromosomal translocation involving this gene is associated with a susceptibility to developmental dyslexia. Mutations in this gene are associated with deficits in reading and spelling. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the downstream cell cycle progression 1 (CCPG1) gene.

• Partner Proteins:

  SPDL1; KDM1A; Stub1; Hspa1b; GABARAPL1; GABARAP; HSPA1A

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 92%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  48kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  420

• NCBI Gene Symbol:

  DNAAF4

• Protein Name:

  Dynein assembly factor 4, axonemal

• Nucleotide Accession Number:

  NM_130810