SETMAR Antibody - C-terminal region: HRP (ARP51245_P050-HRP)

• Gene Name:

  SET domain and mariner transposase fusion gene

• Gene Aliases:

  Mar1, METNASE

• Gene ID:

  6419

• Swiss Prot:

  E7EN68

• Accession Number:

  NP_001230652

• Host:

  Rabbit

• Reactivity:

  Human, Cow

• Immunogen:

  The immunogen is a synthetic peptide directed towards the C-terminal region of Human SETMAR

• Target:

  This gene encodes a fusion protein that contains an N-terminal histone-lysine N-methyltransferase domain and a C-terminal mariner transposase domain. The encoded protein binds DNA and functions in DNA repair activities including non-homologous end joining and double strand break repair. The SET domain portion of this protein specifically methylates histone H3 lysines 4 and 36. This gene exists as a fusion gene only in anthropoid primates, other organisms lack mariner transposase domain.

• Partner Proteins:

  CHEK1; H3F3C; tat; PRPF19; SETMAR; RAD9A; PCNA; TOP2A; XRCC4

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Human: 100%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  59kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  545

• NCBI Gene Symbol:

  SETMAR

• Protein Name:

  Histone-lysine N-methyltransferase Ensembl ENSP00000403145