MAP2K7 Antibody - C-terminal region: Biotin (ARP49026_P050-Biotin)

• Gene Name:

  Mitogen-activated protein kinase kinase 7

• Gene Aliases:

  MEK, MKK7, JNKK2, MEK 7, MAPKK7, PRKMK7, SAPKK4, SAPKK-4

• Gene ID:

  5609

• Swiss Prot:

  O14733-2

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the C-terminal region of Human MP2K7

• Target:

  The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase specifically activates MAPK8/JNK1 and MAPK9/JNK2, and this kinase itself is phosphorylated and activated by MAP kinase kinase kinases including MAP3K1/MEKK1, MAP3K2/MEKK2, MAP3K3/MEKK5, and MAP4K2/GCK. This kinase is involved in the signal transduction mediating the cell responses to proinflammatory cytokines, and environmental stresses. Alternative splicing results in multiple transcript variants.

• Partner Proteins:

  MAPK8; MAP3K3; MAP3K2; UBC; FBXO6; MAP3K11; MAPK8IP1; LPXN; VRK2; RPL30; MAPK9; HSP90AA1; ATF4; JUN; WDR6; BCL10; MAP2K4; MAPK1; LRRK2; MAP3K4; MAP3K1; MYC; ELAVL1; ALK; DUSP22; DUSP19; MAPK8IP3; CNKSR1; ZAK; TRIB1; MAPK8IP2; GADD45B; CFLAR; MAP2K7; MAP3K

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 93%; Zebrafish: 93%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  50kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  462

• NCBI Gene Symbol:

  MAP2K7

• Protein Name:

  Dual specificity mitogen-activated protein kinase kinase 7