LAPTM4B Antibody - middle region: Biotin (ARP47442_P050-Biotin)

• Gene Name:

  Lysosomal protein transmembrane 4 beta

• Gene Aliases:

  LC27, LAPTM4beta

• Gene ID:

  55353

• Swiss Prot:

  Q86VI4-3

• Accession Number:

  NP_060877

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human LAPTM4B

• Target:

  LAPTM4B is a multi-pass membrane protein. It belongs to the LAPTM4/LAPTM5 transporter family. LAPTM4b has active role in disease progression of malignant cells and is involved in cell proliferation and multidrug resistance. The genetic polymorphism of LAPTM4B is a potential risk factor for the development of colon cancer and gastric cancer. The research results also indicated that LAPTM4B may be a clinically useful prognostic indicator for ovarian carcinoma and may play a role in human hepatocellular carcinoma.

• Partner Proteins:

  NAALADL2; TFRC; NEDD4; UBC

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  IHC, WB

• Purification:

  Affinity Purified

• Sample Type:

  There is BioGPS gene expression data showing that LAPTM4B is expressed in HEK293T

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 93%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  35kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  317

• NCBI Gene Symbol:

  LAPTM4B

• Protein Name:

  Lysosomal-associated transmembrane protein 4B

• Nucleotide Accession Number:

  NM_018407