LETM1 Antibody - middle region: HRP (ARP46881_T100-HRP)

• Gene Name:

  Leucine zipper and EF-hand containing transmembrane protein 1

• Gene Aliases:

  SLC55A1

• Gene ID:

  3954

• Swiss Prot:

  O95202

• Accession Number:

  EAW82560

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human LETM1

• Target:

  This gene encodes a protein that is localized to the inner mitochondrial membrane. The protein functions to maintain the mitochondrial tubular shapes and is required for normal mitochondrial morphology and cellular viability. Mutations in this gene cause Wolf-Hirschhorn syndrome, a complex malformation syndrome caused by the deletion of parts of the distal short arm of chromosome 4. Related pseudogenes have been identified on chromosomes 8, 15 and 19.

• Partner Proteins:

  PSMA3; UBC; LATS2; C12orf57; SYNCRIP; ILF3; TBK1; ICT1

• Clonality:

  Polyclonal

• Conjugation:

  HRP: Horseradish Peroxidase

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Sample Type:

  LETM1 is strongly supported by BioGPS gene expression data to be expressed in Jurkat

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 86%; Rat: 100%

• Format:

  Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  60kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  559

• NCBI Gene Symbol:

  LETM1

• Protein Name:

  Mitochondrial proton/calcium exchanger protein

• Nucleotide Accession Number:

  NM_012318