VARS Antibody - middle region: Biotin (ARP46151_P050-Biotin)

• Gene Name:

  Valyl-tRNA synthetase

• Gene Aliases:

  G7A, VARS, VARS2, NDMSCA

• Gene ID:

  7407

• Swiss Prot:

  P26640

• Accession Number:

  NP_006286

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Yeast, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human VARS

• Target:

  Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. VARS belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex.Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. The protein encoded by this gene belongs to class-I aminoacyl-tRNA synthetase family and is located in the class III region of the major histocompatibility complex. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

• Partner Proteins:

  CALCOCO2; SUMO2; SART3; STAU1; UBC; EED; CCT4; KNTC1; AIMP1; CCT3; QARS; EEF1G; EEF1D; EEF1B2; FBXO6; YWHAQ; MAPK11; VCAM1; ITGA4; FN1; LARS; CAD; UBD; SHC1; CUL3; CDK2; CHD7; CACNA1A; ATG101; OTUD5; DMWD; EEF1A1; EEF1A2; TRAF6; TFE3; HLA-B; EPB41

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC

• Purification:

  Affinity Purified

• Sample Type:

  VARS is strongly supported by BioGPS gene expression data to be expressed in 721_B

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 93%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Yeast: 86%; Zebrafish: 86%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  140kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  1264

• NCBI Gene Symbol:

  VARS

• Protein Name:

  Valine--tRNA ligase

• Nucleotide Accession Number:

  NM_006295