HIST1H1C Antibody - middle region: FITC (ARP46122_P050-FITC)

• Gene Name:

  Histone cluster 1, H1c

• Gene Aliases:

  H1C, H1.2, H1F2, H1s-1, HIST1H1C

• Gene ID:

  3006

• Swiss Prot:

  P16403

• Accession Number:

  NP_005310

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the middle region of human HIST1H1C

• Target:

  Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures.Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

• Partner Proteins:

  UBC; CEP250; ATRX; HIST1H3A; LEO1; PAF1; CUL4A; POLR2A; MDM2; ASB16; ASB9; SUZ12; EED; RNF2; APEH; SEC24D; TBCD; PARK2; VHL; UBD; ICAM1; CD81; IGSF8; EIF2AK2; ITGA4; IL7R; CSNK2A2; SMURF1; HIST1H2AD; H1FX; COPS5; CAND1; CUL1; CUL2; CUL3; CUL4B; CUL5; NEDD

• Clonality:

  Polyclonal

• Conjugation:

  FITC: Fluorescein Isothiocyanate

• Type:

  Polyclonal Antibody

• Applications:

  CHIP, WB

• Purification:

  Affinity Purified

• Sample Type:

  HIST1H1C is supported by BioGPS gene expression data to be expressed in 721_B

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 86%; Dog: 86%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 86%; Rabbit: 85%; Rat: 86%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  21kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  213

• NCBI Gene Symbol:

  HIST1H1C

• Protein Name:

  Histone H1.2

• Nucleotide Accession Number:

  NM_005319