EIF2S3 Antibody - N-terminal region: Biotin (ARP46057_P050-Biotin)

• Gene Name:

  Eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa

• Gene Aliases:

  EIF2, EIF2G, MEHMO, MRXSBRK, eIF-2gA, EIF2gamma

• Gene ID:

  1968

• Swiss Prot:

  P41091

• Accession Number:

  NP_001406

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

• Immunogen:

  The immunogen is a synthetic peptide directed towards the N terminal region of human EIF2S3

• Target:

  EIF-2 functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.

• Partner Proteins:

  UBC; RNF2; rev; CCAR2; PLD3; EEF1E1; AIMP1; AIP; IQGAP1; RARS; QARS; IMPDH2; DNAJA1; EIF2S1; MAPK6; TARDBP; FN1; UBD; GRK5; CAND1; CDK2; SUMO1; ELAVL1; SUMO2; NDRG1; RAD21; HDGF; DCC; METAP2; EIF1B; CASP4; H3F3A; CTCF

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  51kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  472

• NCBI Gene Symbol:

  EIF2S3

• Protein Name:

  Eukaryotic translation initiation factor 2 subunit 3

• Nucleotide Accession Number:

  NM_001415