Fbxl3 Antibody - C-terminal region: Biotin (ARP43099_P050-Biotin)

• Gene Name:

  F-box and leucine-rich repeat protein 3

• Gene Aliases:

  Ov, FBK, Fbl, Pla, Fbxl, Ovtm, Fbl3a, Fbxl3a, Play68, AU041772, AW212966

• Gene ID:

  50789

• Swiss Prot:

  Q8C4V4

• Accession Number:

  NP_056637

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Sheep, Zebrafish

• Target:

  Fbxl3 is a substrate-recognition component of some SCF (SKP1-CUL1-F-box protein) -type E3 ubiquitin ligase complex involved in circadian clock function. The SCF (FBXL3) complex acts by mediating ubiquitination and subsequent degradation of CRY1 and CRY2. Recruiter of target protein that may recognize and bind to some phosphorylated proteins and promotes their ubiquitination and degradation.

• Partner Proteins:

  Skp1a; Cry2; Cry1

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 86%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  49kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  428

• NCBI Gene Symbol:

  FBXL3

• Protein Name:

  F-box/LRR-repeat protein 3

• Nucleotide Accession Number:

  NM_015822