HERC4 Antibody - N-terminal region: Biotin (ARP42990_P050-Biotin)

• Gene Name:

  HECT and RLD domain containing E3 ubiquitin protein ligase 4

• Gene ID:

  26091

• Swiss Prot:

  Q5GLZ8

• Accession Number:

  AAV66578

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Zebrafish

• Immunogen:

  The immunogen is a synthetic peptide directed towards the n terminal region of human HERC4

• Target:

  HERC4 belongs to the HERC family of ubiquitin ligases, all of which contain a HECT domain and at least 1 RCC1 (MIM 179710) -like domain (RLD) . The 350-amino acid HECT domain is predicted to catalyze the formation of a thioester with ubiquitin before transferring it to a substrate, and the RLD is predicted to act as a guanine nucleotide exchange factor for small G proteins.

• Partner Proteins:

  UBC; SUMO2; H2AFV; DCTPP1; C9orf78; NT5C2; FKBP9; NUBP2; USP5; WARS; RAD23A; PCNA; HEXA; HSP90AA1; UBE2J2; UBE2E3; UBE2D2; HERC4; HERC6

• Clonality:

  Polyclonal

• Conjugation:

  Biotin

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification:

  Affinity Purified

• Concentration:

  0.5 mg/mL

• Homology:

  Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 93%; Rat: 100%; Zebrafish: 83%

• Format:

  Liquid. Purified antibody supplied in 1x PBS buffer.

• Reconstitution:

  All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

• Molecular Weight:

  13kDa

• Shipping Conditions:

  Wet Ice

• Protein Length:

  117

• NCBI Gene Symbol:

  HERC4

• Protein Name:

  Probable E3 ubiquitin-protein ligase HERC4

• Nucleotide Accession Number:

  NM_015601